Imodzi mwa ma antibayotiki otchuka komanso othandiza kwambiri ndi Ceftriaxone, omwe zotsatira zake ziyenera kuphunzitsidwa mosamala monga momwe zizindikiro zisanagwiritsire ntchito. Ganizirani zomwe muyenera kuzichita mukamapereka chithandizo ndi mankhwalawa.
Zovuta za Ceftriaxone
Kudyetsa ma antibiotic kungaperekedwe ndi mayendedwe olakwika, omwe ndi: urticaria, kuyabwa ndi kuthamanga. Nthawi zambiri, pali exudative erythema multiforme, bronchospasm kapena anaphylactic shock.
Ziwalo za m'mimba zimatha kuthandizira kumwa mankhwala ndi kutsekula m'mimba, kapena mosemphana ndi kudzimbidwa, komanso kunyozetsa, kuphwanya kukoma mtima. Nthawizina zotsatira za mankhwalawa a Ceftriaxone amawonetsedwa ngati glossitis (kutupa kwa lilime) kapena stomatitis (zilonda zopweteka pamlomo mucosa). Odwala akhoza kudandaula za ululu m'mimba (ali ndi khalidwe losatha).
Makamaka, chiwindi chimayendera ku ceftriaxone: ma transaminases angapangitse ntchito, komanso alkaline phosphatase kapena bilirubin. Nthawi zina, n'zotheka kupanga pseudocholithiasis ya gallbladder kapena cholestatic jaundice.
Zotsatira za impso
Malinga ndi malangizo, zotsatira za Ceftriaxone zingakhale zophwanya impso, chifukwa momwe magazi amachokera:
- mankhwala osakaniza amadzimadzi (azotemia);
- creatinine (hypercreatininaemia);
- urea.
Mu mkodzo, pangakhale, pakhoza kukhala:
- shuga (glucosuria);
- magazi (hematuria);
- zotchedwa zinyalala - nkhungu za mapuloteni kapena zinthu zam'manja (cylindruria).
Kuchuluka kwa mkodzo wobisika ndi impso kungachepetse (oliguria) kapena kufika ku zero (anuria).
Zochita za hematopoietic dongosolo
Pa ziwalo za kukhazikitsidwa kwa magazi, majekeseni a Ceftriaxone angakhalenso ndi zotsatirapo, zomwe zimapangitsa kuchepa kwa gawo la magazi lazigawo:
- zofiira (erythrocytes) - kuchepa magazi m'thupi ;
- zoyera (leukocyte) - leukopenia;
- leutrophilic leukocytes - neutropenia;
- granulocytes - granulocytopenia;
- lymphocytes - lymphocytopenia;
- thrombocytes - thrombocytopenia.
Mitundu ya m'magazi yotsekemera m'magazi imatha kuchepa, chithokomiro chikhoza kuchitika (kusowa kochepa kwa magazi), komwe kumadzaza ndi magazi.
Pa nthawi yomweyo, nthawi zina zotsatira za Ceftriaxone ndi leukocytosis, kuwonjezeka kwa magazi a matupi oyera.
Zomwe amachitira kumidzi ndi zina
Pamene antibiotic imayikidwa mu mitsempha, kutupa kwa khoma (phlebitis) kungapangitse, kapena wodwalayo angoyamba kumva ululu panthawi ya chotengera. Pamene mankhwalawa akuyendetsedwa bwino, nthawi zina zimakhala zopweteka komanso zopweteka mu minofu.
Zotsatira zosafunika kwenikweni za maofesi a Ceftriaxone ndi awa:
- mutu;
- Candidiasis ;
- chizungulire;
- kutuluka m'mphuno;
- Kupititsa patsogolo mankhwala (kuyambitsa kukana mankhwala omwe amachititsa kuti kachilombo kamene kamere kukula).
Kuwonjezera pa mankhwala ndi mankhwala
Ngati mwadodometsa kwambiri, mankhwala opatsirana amachitidwa. Palibe mankhwala enieni omwe amachotsa zotsatira za Ceftriaxone; hemodialysis ilibe ntchito. Choncho,
Ceftriaxone imakhala ndi zovuta zina: zimapangitsa kuti vitamini K isapangidwe, chifukwa, ngati mankhwala ena aliwonse a antibiotic, imachotsa matumbo a m'mimba, choncho ndiyomwe sayenera kutenga mankhwala osagwiritsidwa ntchito poletsa kutupa - izi zingapangitse ngozi yoika magazi. Mankhwalawa sagwirizana ndi ethanol, choncho kumwa mowa panthawi ya mankhwala kumatsutsana.
Aminoglycosides ndi Ceftriaxone, akuchita limodzi, kuwonjezera zotsatira za wina ndi mzake (synergy) motsutsana ndi tizilombo toyambitsa magalamu.