Ngakhale kuchepa pang'ono mu chithokomiro kumabweretsa mavuto aakulu. Mlingo wa TPO, michere, wopangidwa ndi gland, umaphunziridwa mu matenda ambiri. Mu thupi labwino zinthu izi siziripo kapena chiwerengero chawo chachepetsedwa, koma chiwerengero chawo chikukula ndi matenda a chitetezo cha mthupi, omwe ana ndi abambo azimayi nthawi zambiri amakumana nawo. Kuti matendawa atengedwe pakati pa amayi, ngakhale kusiyana kwakukulu kwa ma antibodies a TPO n'kofunikira.
Mlingo wamagulu a antibodies ku TPO
Kuti mudziwe momwe chithokomiro chikuyendera, wodwalayo akulimbikitsidwa kuti ayese. Monga chidziwitso, magazi a mitsempha, omwe amaperekedwa m'mawa pamimba yopanda kanthu, amagwiritsidwa ntchito. Zisonyezo za kafukufuku zingakhale zochitika zotere:
- kufotokoza kwa matenda a hypothyroidism ndi hyperthyroidism;
- goiter;
- kupuma kwa miyendo;
- musanayambe kumwa mankhwala omwe amakhudza chithokomiro;
- mu kuphunzira za infertility;
- Matenda okhaokha (vasculitis, lupus, shuga).
Powerenga ma antibodies ku chithokomiro peroxidase (TPO), chikhalidwe chimakhala kuyambira 0 mpaka 35 U / L kwa anthu osapitirira zaka 50. Pa anthu oposa 50 omwe amatsutsana ndi TPO ayenera kusungidwa kuchoka ku zero kupita ku magawo 100 / lita imodzi.
Tiyenera kudziwa kuti pafupifupi 10% odwala ali ndi vuto la chithokomiro ali ndi kachilombo kochepa. Izi zimakhala zovuta kwambiri kwa anthu omwe akudwala matenda a rheumatic.
Ngati ma antibodies ku TPO ndi apamwamba kusiyana ndi achibadwa
Kupitiliza chizindikirocho ndi kotheka chifukwa cha zinthu izi:
- Hashimoto's thyroiditis (matenda oposa 90%), omwe ma antibodies ali ndi maselo a chithokomiro;
- Matenda a Manda ;
- chithandizo;
- Matenda a Croven.
Ziyenera kuzindikiritsidwa ndi zina zomwe sizikhudzana ndi TVET:
- chilengedwe choipa;
- chisokonezo;
- kupweteka kwamakono kwa chithokomiro;
- chithandizo cha nthawi yaitali ndi njira yamadzimadzi;
- adatengera matenda a tizilombo.
Ngati mankhwala opatsirana pogwiritsa ntchito mankhwala opatsirana pogwiritsa ntchito mankhwala a TPO amaposa chizoloŵezi cha amayi pachigawo chogonana, chiwopsezo cha chithokomiro pambuyo pobereka chimakhala chachikulu. Kuwonjezera pamenepo, zofanana ndizo zingasokoneze chitukuko cha mwanayo. Kuwonjezeka kwa chiwerengero cha ma antibodies kumafotokozedwa ndi hypothyroidism , zomwe zimaipitsa kaphatikizidwe ka mahomoni. Kuopsa kwa matendawa kwa ana ndikuti m'tsogolomu kumabweretsa cretinism.