Kuti tipeze zomwe zimachitika pa hCG pa nthawi ya mimba tidzatha kudziwa zomwe hCG ndi ndondomeko yake. Mankhwala otchedwa chorionic gonadotropin (hCG) ndi hormone yopangidwa ndi chithunzithunzi cha amayi omwe ali ndi pakati pomwe ali ndi mimba ndi chiberekero asanabadwe. HCG ilipo mu thupi la munthu ndipo silingathe kutenga mimba, koma imakhala yochepa kwambiri. Mbali yapamwamba yomwe imapezeka mwa amayi osakhalapo kapena mwamuna imasonyeza njira zowonongeka m'thupi. Pakati pa mimba, masiku 7-10 atatha kutenga mimba, mlingo wa beta-hCG ukuwonjezeka ndipo ukhoza kutsimikiziridwa. Kawirikawiri beta-hCG imadutsa masiku awiri, nsonga yake imagwera pa masabata 7-11, ndipo imapita patsogolo. Ndibwino kuti muwonetsere 1 trimester pa masabata khumi ndi asanu ndi awiri (10-14) a mimba, hCG mitengoyi kuyambira 200,000 mpaka 60,000 mU / ml, imachitidwa kuti mudziwe mavuto oyambirira a mimba kapena zovuta za congenital pathologies za mwanayo.
Mlingo wa hCG kwa amayi apakati
Kufunika kwa HCG ya hormoni n'kovuta kwambiri: imapangidwa ndi thupi, limathandiza kuti thupi lachikasu lisakhalepo kwa milungu iwiri monga nthawi yomwe amayamba kumaliseche, koma nthawi yonse yothandizira. HCG ili ndi magawo awiri - alpha ndi beta. Kufufuza kumatengedwa ndi sampuli ya magazi. Pogwiritsa ntchito mawu ang'onoang'ono, mtundu wapadera wa HCG wa magazi umagwiritsidwa ntchito, chizoloŵezi cha mimba ndi 1000-1500 IU / l. Ngati nthenda ya hCG iposa 1500 IU / L, dzira la fetus m'kati mwa uterine liyenera kuwonetsedwa bwino ndi kuyesedwa kwa ultrasound.
Ngati hCG ndi yapamwamba kuposa yachibadwa mimba, imatha kunena za toxicosis, matenda a Down kapena matenda ena a fetus , matenda a shuga, amayi apakati, nthawi yolakwika ya mimba. Komanso, machitidwe a hCG muwiri, machitidwe a hCG pa mimba iliyonse yowonjezera imakula mofanana ndi chiwerengero cha mazira.
Ngati HCG ndi yochepa kusiyana ndi yachibadwa mimba, izi zingasonyeze kuchedwa kwa kukula kwa fetus, kusakwanira kosayembekezereka, mimba yosakonzekera kapena imfa ya mwana wamwamuna. Chizoloŵezi cha hCG ndi ectopic mimba ndi zoposa 1500 mIU / ml, ndipo dzira la fetus mu chiberekero cha uterine sichidziwika.
Kufufuza kwa hCG pa nthawi ya mimba - chizoloŵezi
Pakuyezetsa magazi pa b hchch pa mimba chizoloŵezi chimapanga:
- kwa masabata 1-2 - kuyambira 25 mpaka 300 mU / ml;
- Masabata 2-3 - kuyambira 1500 mpaka 5000 mU / ml;
- pa masabata 3-4 - kuyambira 10,000 mpaka 30,000 mU / ml;
- pa masabata 4-5 - kuchokera 20,000 mpaka 100,000 mU / ml;
- pa masabata 5-6 - kuchokera 50,000 mpaka 200,000 mU / ml;
- pa masabata 6-7 - kuchokera 50,000 mpaka 20,000 mU / ml;
- pa masabata 7-8 - kuyambira 200,000 mpaka 200,000 mU / ml;
- pa masabata 8 mpaka 9 - kuchokera 200,000 mpaka 100,000 mU / ml;
- pa masabata 9-10 - kuchokera 200,000 mpaka 95,000 mU / ml;
- pa masabata 11-12 - kuyambira 200,000 mpaka 90,000 mU / ml;
- pa sabata 13-14 - kuyambira 15,000 mpaka 60,000 mU / ml;
- pa sabata la 15-25 - kuyambira 10,000 mpaka 35,000 mU / ml;
- pa sabata 26-37 - kuyambira 10,000 mpaka 60,000 mU / ml.
Dziwani kuti panthawi yoyezetsa, hCG imatanthawuzira pafupifupi monga chiwalo chilichonse chili ndi makhalidwe ake ndipo zotsatira zake zingatheke pang'ono.
HCG - zikhalidwe za IVF
Miyambo ya HCG pambuyo pa IVF nthawi zambiri imakhala yapamwamba kwambiri kusiyana ndi kubadwa mwa njira zowoneka, popeza kuti thupi lisanafike, thupi la mkazi limakhala lodzaza ndi mahomoni kuti akonze zamoyo kuti abereke komanso kubereka mwanayo. Choncho, zimakhala zovuta kudziwa mapasa kapena katatu pambuyo pa mavitamini. Koma ngati zotsatira zake zikuposa kukula kwa hCG ndi 1.5 kapena 2 - mukhoza kukonzekera kubadwa kwa mapasa kapena katatu.
Chizoloŵezi cha hCG pa nthawi ya mimba ya IOM
Pambuyo popeza zotsatira za kusanthula kwa hCG, coefficient yotchedwa MOM imawerengedwa, yomwe imagwiritsidwa ntchito kuwerengetsa zizindikiro zoopsa. Amawerengedwa monga chiŵerengero cha hCG mu seramu kufunika kwapakati pa nthawi yogonana. Chizoloŵezi cha hCG pa nthawi ya mimba ya IOM ndi chimodzi.
Malinga ndi zotsatira zomwe zapezeka muyeso yoyamba ya mayesero, n'zotheka kudziwa ngati mayi wakhanda ali pachiopsezo cha chromosomal pathologies ndi congenital anomalies. Musanayambe, yochenjezani za mavuto omwe angakonzekere kapena kukonzekeretsa mayi wamtsogolo kuti abereke mwana wathanzi.