Wothandizira mankhwala a syphilis ndi zamoyo zamoyo zazikuluzikulu, zotchedwa treponema ( Treponema pallidum ). Chifukwa cha microbiology, sayansi ya tizilombo ting'onoting'ono, tapezeka kuti treponema yotumbululuka ndi gram-negative spirochete. Thupi lake likukwera, lakuda ndi kupindika. Kutalika kwa thupi kumasiyanasiyana kuyambira 4 mpaka 14 μm, ndipo kukula kwake kwa mtanda ndi 0.2-0.5 μm. Ngakhale kuti ukuluwo ndi wolemera kwambiri, wothandizira mankhwala a syphilis ndi tizilombo toyambitsa matenda. Ndipo chifukwa chakuti pamwamba pa thupi lopanda kanthu imapanga mankhwala a mucopolysaccharide, ndizovuta kuti zikhale zopwetekedwa ndi mapegocyte ndi ma antibodies.
Dzina lakuti "wotumbululuka" treponema latengedwa kuchokera ku malo apadera omwe sangayenere kuyambitsidwa ndi utoto wapadera wa mabakiteriya. Treponema ya Pale sakhala kunja kwa thupi la munthu. Kwa kafukufuku amatha kusiyanitsa kokha ndi zovuta za munthu wodwala. Njira yabwino yopambitsira chitukuko cha spirochetes ndizoyera.
Tizilombo toyambitsa matenda tizilombo toyambitsa matenda timene timayambitsa matenda a syphilis
Chifukwa cha maphunziro ochepa kwambiri, kuwonjezera pa mawonekedwe a mawonekedwe otchedwa treponema, granular (chiti) ndi L-mawonekedwe adakhazikitsidwa. Zimaganiziridwa kuti chitsipi ndi L-mawonekedwe ndi mwana wamkazi. Pa chitukuko cha intracellular, mawonekedwe a mawonekedwe otchedwa treponema amafa. Envulopu ya selo yowonongeka ndipo tizilombo toyambitsa matenda tikumenyana ndi maselo ena omwe amalowa.
Kodi mungatani kuti muwononge kampani ya causative - yotumbululuka?
Mtundu wotchedwa spirochaete (treponema) umaphedwa ndi mankhwala ophera tizilombo toyambitsa matenda. Zimakhudzidwa ndi ma antibayotiki ena - Tetracycline, Erythromycin, Penicillin, komanso Arsenobenzolam. Mwa mitundu yatsopano ya antibayotiki, Cephalosporin imagwiritsidwa ntchito.