Warfarin ndi anticoagulant yachangu, zomwe zimachokera ku coumarin. Mankhwalawa amachititsa kuti chiwerengero cha mavitamini-K chikhale chodalira. Kuchuluka kwa zinthuzi kwafupika ndipo, motero, magazi a coagulability amachepetsedwa. Mlingo pamene mutenga Warfarin ayenera kukhala yolondola. Kuonjezerapo, odwala omwe amamwa mankhwalawa amafunika kuyesa magazi nthawi zonse kuti azindikire kuti INR (magazi, omwe amaimira coagulability). Kuchulukanso kapena kudya kosafunika kwa warfarin kungayambitse magazi m'magazi ndi zotsatira zina za kusiyana kwakukulu, mpaka zotsatira zompha.
Zotsatira Zachisoni za Warfarin
Panthawi ya chithandizo cha mankhwala, zotsatirazi zikhoza kuchitika:
- Kusuta - nthawi zambiri kukumana ndi ntchito ya Warfarin. Mwachizoloŵezi chingathe kuchepetsedwa ndi chifuwa chokha magazi kapena kupanga mapewa aang'ono pa khungu. Nthawi zambiri, kuchepa kwa magazi m'thupi ndi kachipatala komweko kumapezeka chifukwa cha thrombosis. Kuchuluka kwa thupi, makamaka kuika moyo kwa wodwala, kutaya magazi, ndi kuwona ngati akudwala Warfarin, kumawonekera pafupifupi 1,000 pa 10,000, ndipo nthawi zambiri zimakhudzidwa ndi kukhalapo kwa matenda oopsa komanso zovuta zina.
- Kuchokera m'magazi amatha kuchepetsa kunyowa, kutsegula m'mimba, kusanza, kupweteka m'mimba. Nthawi zambiri - kukula kwa jaundice.
- Mbali ya mitsempha ya mitsempha, nthawi zambiri, pangakhale kuwonjezeka kutopa, kupweteka mutu, chizungulire, ndi kusokonezeka maganizo.
- Muzochitika zosayembekezereka kwambiri ndi chithandizo cha nthawi yaitali ndi warfarin, pali zovuta kuchokera ku dongosolo la kupuma: tracheal kapena tracheo-bronchial calcification.
- Ndi kutsekemera kwa munthu aliyense kapena kusagwirizana kwa mankhwala, khungu la khungu, kuyabwa, dermatitis, vasculitis , alopecia (tsitsi lotayika) lingakhoze kuwonedwa.
Overdose Warfarin
Kuwathandiza kuchiza mlingo wa mankhwala kumayandikira kukhetsa magazi, chifukwa chake kulamulidwa kwa INR ndi kutsata ndondomeko yoyenera pa chithandizo cha warfarin kumawathandiza kwambiri. Ndi mankhwala ochepa, nthawi zambiri mankhwalawa amathamanga kapena mlingo wafupika. Ngati kumwa mopitirira muyeso kumayambitsa chitukuko chokhala ndi magazi ambiri, gwiritsirani ntchito vitamini K (kusokoneza zotsatira za Warfarin), komanso madzi a m'magazi atsopano kapena a coagulation factor concentrates.
Kulamulira kwa INR pamene mutenga Warfarin
MNO ndi chiŵerengero cha mayiko padziko lonse, chinthu chotseketsa, chomwe chiwerengedwa kuchokera ku ndondomeko ya prothrombin. Kuposa chizindikiro ichi ndi chochepa, magazi ndi owopsa ndipo pali ngozi yambiri ya magazi. MNO yapamwamba imasonyeza kuika magazi. Pa nthawi yoyamba, posankha mlingo woyenera wa mankhwala, chizindikirocho chimayesedwa tsiku ndi tsiku. M'tsogolomu tikulimbikitsidwa kuti tichite kafukufuku kamodzi pa sabata, ndipo ngati miyeso 3-4 imakhalabe mkati mwa chizolowezi chovomerezeka, nthawi zambiri mayendedwe a INR akhoza kuchepetsedwa kamodzi pa masabata awiri. Kusanthula kwina ku INR kumafunikanso ngati kusintha kwa zakudya, nkhawa, ndi zina zomwe zingakhudze chizindikiro.
Chakudya pamene mutenga Warfarin
Zakudya zomwe zili ndi vitamini K zambiri zimachepetsa mphamvu ya mankhwala. Mavitamini ambiriwa amapezeka maluwa atsopano, choncho mankhwalawa sayenera kuzunzidwa ndi mankhwala monga:
- peyala;
- kabichi;
- anyezi;
- cilantro;
- parsley;
- nkhaka (makamaka kutsukidwa, popeza mavitamini amapezeka makamaka pakhungu), chicory;
- timbewu;
- kiwi zipatso;
- saladi;
- mafuta;
- nandolo;
- soya;
- pistachios;
- zofiira;
- sipinachi.
Warfarin ndi mowa
Mowa umalimbitsa zotsatira za antifaragin ndi zotsatira zake, kuchitika kwa magazi osakhazikika kungakhaleko ngakhale ndi zovuta zapakhomo. Kutenga mowa waukulu wa mowa pamodzi ndi warfarin wadzazidwa ndi kukula kwa magazi mkati, makamaka mmimba, yomwe ili pangozi.