Nthawi yayitali mu vitro mwana wa chikhalidwe

Kutha kwa mazira a mavitamini nthawi yaitali (LTC-BS - Kulima Kwambiri kwa Blastocyst Stage) ndi njira yomwe cholinga chake chachikulu ndicho kukhala ndi chizoloŵezi chokhala ndi mazira onse, asanalowe mu uterine ndi IVF. Izi ndizomwe zimakhala zochepa pa nthawi ndipo zimatha masiku 6 okha. Pambuyo pake, kamwana kameneka kamayenera kuikidwa mu chiberekero chokonzekera mu endometrium.

Kodi njira iyi ndi yotani?

Kulimbitsa thupi kwa nthawi yayitali kumakhala kofunika kwambiri komanso njira yovuta yomwe imafuna labotale yapadera, zipangizo zamakono. Izi zikuwonetseratu kuti palibe malo onse omwe amapezeka mu IVF ndipo kupanga mimba kumapereka njirayi.

Njirayi ikuphatikizapo kulima mazira asanayambe blastocyst. Njira zam'mbuyomu zomwe zimagwiritsidwa ntchito kale zimalimbikitsa kupatsirana kwa mwana wosabadwa m'thupi la mkazi pa siteji ya kugawidwa kwake, mwachitsanzo, mu masiku 2-3. Izi zathandiza kuchepetsa ubwino wa IVF ndipo njira yowatengera mwanayo imayenera kubwerezedwa nthawi zambiri.

Kusintha kwa mazira mu vitro kwachititsa kuti pakhale njira zamakono mu embryology, chifukwa cha zochitika zapadera zokhudza mankhwala opatsirana. Njira imeneyi, yomwe imagwiritsidwa ntchito popititsa patsogolo zipatala, imakhudza nthawi yayitali ndi mazira apadera (SICM / SIBM ndi Embryo Assist / Blast Assist).

Ndiyeneranso kukumbukira kuti njirayi sitingathe kukhalapo popanda kugwiritsa ntchito chipangizo chapadera - chotsitsimutsa magetsi. Zili mkati mwake kuti zygotes zingapo zimayikidwa pamodzi ndi zakudya zowonjezera. Pambuyo masiku 4-6, akatswiri amachotsa blastocyst kuchokera pa chipangizochi ndikuyesa kuti imatha. Malingana ndi chiwerengero cha chiwerengero, pafupifupi 60-70% mazira omwe amamangidwa panthawi ya IVF, n'zotheka kupeza mazira oyenera.

Kodi ubwino wa mazira amatha nthawi yaitali bwanji?

Njira imeneyi ya IVF imalola, choyamba, kukonzanso mtundu wa kusankha (ndikusankha) ndikugwiritsira ntchito mazira omwe ali otsika kwambiri omwe amatchedwa kuti akhoza kuikidwa. Mwa mawu osavuta, kugwiritsa ntchito njirayi kunachulukitsa kwambiri mwayi wa mimba pambuyo pa IVF.

Kuphatikizanso apo, zina mwa ubwino wa kulimbikitsa mimba kwa nthawi yaitali zimatchedwa:

• kuchepa kwa chiwerengero cha chromosomal zosavomerezeka mu mazira omwe amaikidwa mu sitepe ya blastocyst;
• Njirayi imakhala yowonjezera mthupi poyerekeza ndi mluza wopita ku masiku atatu;
• kulima kwa nthawi yaitali kumapangitsa kuti mazira 1-2 akhale mu chiberekero, tk. mwayi wotsatizana ndi chitukuko ndi wapamwamba kwambiri;
• chiopsezo chokhala ndi vuto ngati ectopic pregnancy ndi kuchepa kwambiri.

Kodi zovuta za njira iyi ndi ziti?

Podziwa kuti izi ndizokhalitsa nthawi yayitali ya ma gametes ndi mazira, atanena za ubwino wa njira iyi ya IVF, ndikofunikira kuti musaiwale za zolephera za njira iyi.

Choyamba mwa izi ndi chakuti si mazira onse omwe amakula amakula mpaka blastocyst, nthawi zambiri 50 peresenti ya iwo amafika pa siteji iyi ya chitukuko. Chifukwa cha izi, njira imeneyi ndi yotheka kokha ngati patsiku lachitatu la mbuzi, kulibe osachepera 4. Pa chiwerengero chochepa, mwayi wopezera chinthu chimodzi chokha, kufika pa sitepe ya blastocyst, ndi yotsika kwambiri.

Chosavuta chachiwiri chingathenso kutchedwa nthawi yomwe ngakhale kamwana kamene kakufika pa siteji ya chitukuko chofunikira kuti munthu asamalidwe, izi sizimapereka chitsimikizo chokwanira kuti mbeuyo idzapambana ndipo mimba idzabwera.