Matenda a Alzheimers - amachititsa

Panthawiyi, matenda a Alzheimers amakhudza anthu oposa 50 miliyoni padziko lonse lapansi. M'nkhani ino tidzakambirana za zomwe zimayambitsa matendawa komanso kupewa matenda a Alzheimer ali wamng'ono. Kuphatikiza apo, timalemba zinthu zingapo zomwe zimakhudza kukula kwa matendawa.

Zifukwa za Matenda a Alzheimer

Ngakhale kuti njira zamakono zamankhwala zamakono komanso chitukuko cha matekinoloje atsopano, palibe kumvetsetsa kwathunthu zifukwa zomwe ubongo umakhudzira matendawa. Pali ziphunzitso zitatu zazikulu zomwe zimalongosola kuyambika kwa matendawa:

1. Chidziwitso cha amyloid . Malinga ndi izi, chifukwa cha chitukuko cha matenda a Alzheimer's - chidutswa cha chidutswa cha transmembrane protein chotchedwa beta amyloid. Ndi chimodzi mwa zigawo zikuluzikulu m'mapangidwe a amyloid mu mitsempha ya ubongo pamene chitukukochi chikukula. The gene gene, yomwe imayambitsa mapuloteni kupanga ndi beta-amyloid, ili pa 21 chromosomes ndipo amalimbikitsa kusungunula amyloid ngakhale unyamata. Chochititsa chidwi n'chakuti katemerayu anapangidwa zaka 10 zapitazo, ndipo amatha kupatulira mapiritsi a amyloid m'matumbo a ubongo. Koma, mwatsoka, mankhwalawo sanakhudze kubwezeretsedwa kwa mitsempha yamanjenje ndi momwe ntchitoyo imagwirira ntchito.
2. Cholinergic hypothesis . Anthu ena amakhulupirira kuti matenda a Alzheimer pa achinyamata ndi achikulire amayamba chifukwa cha kuchepa kwa mankhwala a acetylcholine, omwe amachititsa kuti magetsi asokonezeke. Pachifukwa ichi, matenda ambiri a Alzheimer's adakalipobe, ngakhale kuti kafukufuku wina wasonyeza kuti ngakhale mankhwala amphamvu kwambiri omwe amachititsa kuti alibe acetylcholine sagwire ntchito.
3. Tau-maganizo . Mfundo imeneyi ndi yofunika kwambiri mpaka lero ndipo imatsimikiziridwa ndi maphunziro ambiri. Malingana ndi iye, mapuloteni omwe amatha kupanga mapuloteni, omwe amachititsa kupanga mapangidwe a ubongo mkati mwa maselo a mitsempha. Kuphatikizika kwa fungo kumasokoneza kayendetsedwe kake pakati pa neurons, kumakhudza ma microtubules ndi kulepheretsa ntchito yawo.

Kuphatikiza pa mafotokozedwe akuluakulu pa zochitika za matendawa, palinso zifukwa zambiri zomwe zimakhala zosavomerezeka zosawerengeka. Mmodzi wa iwo amachokera ku chitsimikizo chakuti matenda a Alzheimer ndi omwe adalandira. Kafukufuku wa zachipatala akuwonetsa kuti izi sizitsimikiziridwa: kusintha kwa majini pakuyambika kwa matenda omwe ali m'munsiwa kumapezekanso pa 10 peresenti ya milandu.

Kodi mungapewe bwanji Alzheimer's?

Popanda kutsimikizira zolinga, mwachibadwa zimakhala zovuta kukhazikitsa mankhwala okwanira komanso njira zothandizira matenda a Alzheimer's. Ngakhale zili choncho, akatswiri amalimbikitsa kuti azikhala ndi thanzi labwino, lopatsa thanzi, kupatula nthawi yogwiritsa ntchito ubongo komanso kusunga ubongo.

Komanso, zimadziwika kuti kupanga beta-amyloid kungachepetsedwe ndi kudya maapulo ndi madzi a apulo. Komanso, maphunziro ena zaka ziwiri zapitazo asonyeza kuti chiopsezo chotenga matenda a Alzheimer ndi kuchepetsedwa chifukwa cha zakudya za Mediterranean , zobiriwira za polyunsaturated mafuta acids, phosphorus ndi mbewu zonse. Vitamini D , yomwe imapangidwa ndi khungu lopangidwa ndi khungu, imathandizanso kudwala matendawa.

Ndikoyenera kudziwa kuti khofi yachilengedwe, yomwe posachedwapa siidatengedwe ndi zakudya za anthu ambiri, ili ndi zotsatira zothandiza kwambiri pa ubongo ndipo imakhala ngati njira yothetsera matenda omwe ali nawo.