Mankhwala omwenso amagwiritsa ntchito mankhwala osokoneza bongo ndi mankhwala osokoneza bongo omwe amawoneka ngati gulu la ma immunostimulating ndi immunomodulating agents. Amapangidwa kuchokera ku magazi a opereka chithandizo omwe ali ndi mayesero apadera a zachipatala ndi mayeso a ma laboratory ndipo alibe umboni wa matenda opatsirana mwazi (makamaka matenda opatsirana pogonana, chiwindi cha chiwindi ndi B).
Cholinga chachikulu cha mankhwalawa ndi kachigawo kakang'ono kamene kamatulutsa magazi, kamene kamakhala ndi immunoglobulin G ndipo imakhala ndi immunoglobulin M ndi immunoglobulin A yaying'ono. Mankhwala osadziwika a immunoglobulin alibe mavitamini ndi antibiotic, monga stabilizer ali ndi glycine.
Kutulutsidwa kwa mawonekedwe ndi njira yogwiritsira ntchito thupi lodziwika bwino la immunoglobulin
Mankhwalawa angapangidwe ngati njira yothetsera vutoli, ataphatikizidwa mu ampoules, kapena ngati lyophilizate kuti athetse yankho, atapakidwa m'mabotolo. M'mawonekedwe a madzi ali opanda mtundu kapena wachikasu, wowonekera. Kuwongolera kwa thupi lachidziwitso cha immunoglobulin wamtundu woyera ndi loyera kwambiri. Mankhwala a immunoglobulin amagwiritsidwa ntchito poyambitsa matenda (jekeseni) ndi ma intravenous (dropper) administration.
Zida za thupi lodziwika bwino laumunoglobulin
Mankhwalawa ali ndi katundu wa immunoglobulin G, omwe alipo mwa anthu abwino. Mukadziwitsidwa, zotsatira zotsatirazi zikupezeka:
- Kubwezeretsanso kwa ma antibodies omwe akusowa, omwe amathandiza kuchepetsa chiopsezo cha matenda osiyanasiyana;
- kubwezeretsedwa kwa mlingo wochepa wa IgG ku zikhalidwe zoyenera;
- kuwonjezeka kosafunikira kwenikweni kwa thupi la munthu;
- kuponderezana ndi neutralization ya mabakiteriya ambiri, mavairasi ndi ena opatsirana.
Zisonyezero za kugwiritsidwa ntchito kwa thupi lachidziwitso la munthu:
- matenda obwera chifukwa cha matenda osokoneza bongo;
- chiwerengero cha mavitamini;
- imatodenic immunodeficiency;
- matenda aakulu a khansa ya m'magazi;
- myeloma;
- thrombocytopenic purpura ya chitetezo cha mthupi ndi chiopsezo chowonjezeka cha magazi;
- Matenda a Kawasaki;
- kupaka mafuta a mafupa;
- matenda aakulu a chiyambi;
- bakiteriya meningitis;
- Matenda a Guillain-Barre;
- kuwonetsa kutupa kwapachiphuphu kumayimba kosatha;
- hemolytic anemia;
- thrombocytopenia ya chitetezo cha mthupi;
- choyimira;
- selo lofiira laling'ono lapadera la hematopoiesis;
- myasthenia gravis ;
- kuperewera kwadzidzidzi kwadzidzidzi;
- hepatitis A;
- chikuku;
- malingaliro;
- fuluwenza;
- kutsokomola;
- matenda a meningococcal, ndi zina zotero.
Zotsatira zoyipa ndi zosiyana zowonongeka za thupi la munthu
Zotsatirapo za kutenga thupi lodziwika bwino la immunoglobulin:
- kutentha kwa thupi;
- ululu pamutu;
- chisokonezo;
- tachycardia;
- Kufiira pa malo ojambulira;
- thukuta, ndi zina zotero.
Zotsutsana ndi kuyambika kwa thupi lachidziwitso la immunoglobulin:
- hypersensitivity kwa immunoglobulin ya munthu, mankhwala opangidwa ndi magazi;
- Kukhalapo kwa ma antibodies kwa IgA.
Mosamala, mankhwalawa amagwiritsidwa ntchito pamene:
- mimba, kuyamwitsa;
- shuga;
- zovuta zowonongeka;
- kulephera kwa renal;
- nephrite;
- migraines;
- kuperewera kwa mtima kosatha;
- matenda a chitetezo cha m'magazi;
- collagenosis, ndi zina zotero.
Komanso, pogwiritsira ntchito mankhwalawa, akuwona kuti kayendedwe kawo kanthawi kakang'ono kamapangitsa kuti katemera athane ndi matendawa monga rubella, chikuku, mitsempha ndi nkhuku.