Fluoroquinolones ya mbadwo watsopano

Tizilombo ta tizilombo toyambitsa matenda ndi mabakiteriya zimayambitsa matenda oopsa a dongosolo la kupuma, urogenital ndi ziwalo zina za thupi. Fluoroquinolones ya m'badwo watsopano akuwatsutsa bwino. Mankhwalawa amatha kugonjetsa ngakhale matenda osagwirizana ndi quinolones ndi fluoroquinolones, agwiritsidwa ntchito zaka zingapo zapitazo.

Fluoroquinolones 4 mibadwo - ndi mankhwala otani?

Mafluoroquinolones akhala akugwiritsidwa ntchito kuti athetse tizilombo toyambitsa matenda kuyambira m'ma 1960, panthawi yomwe mabakiteriya amawoneka kuti alibe mankhwala ambiri mwa mankhwalawa. Ndi chifukwa chake asayansi samayima pamenepo ndikupanga mankhwala atsopano ndi atsopano, kuwonjezera mphamvu zawo. Nawa maina a mafuko otsiriza a fluoroquinolones ndi otsogolera awo:

1. Kukonzekera kwa m'badwo woyamba (nalidixic acid, oxolinic acid).
2. Mankhwala osokoneza bongo achiwiri (lomefloxacin, norfloxacin, ofloxacin, pefloxacin, iprofloxacin).
3. Kukonzekera kwa m'badwo wachitatu (levofloxacin, parfloxacin).
4. Kukonzekera kwa m'badwo wachinayi (moxifloxacin, hemifloxacin, gatifloxacin, sitafloxacin, trovafloxacin).

Zochita za mbadwo watsopanowu wa fluoroquinolones zimadalira kuikidwa kwawo ku bacteria DNA, momwe zimakhala zochepa kuti zikhoza kuchulukana ndi kufa msanga. Ndi mbadwo uliwonse, chiwerengero cha bacilli zomwe zimayambitsa mankhwala osokoneza bongo chikuwonjezeka. Mpaka pano, izi ndi izi:

• E. coli;
• Pseudomonas aeruginosa ;
• gnofilnaya ndodo;
• shigella;
• salmonella;
• chomera;
• hominococci;
• meningococci;
• Campylobacter;
• chlamydia;
• mycoplasma;
• pneumococci;
• staphylococci .

Nzosadabwitsa kuti ambiri a fluoroquinolones ali pa mndandanda wa mankhwala ofunikira komanso ofunikira - popanda iwo n'zosatheka kuchiza chibayo, kolera, TB ndi matenda ena owopsa. Tizilombo tokha omwe mankhwalawa sungakhudze ndi mabakiteriya onse a anaerobic.

Kodi fluoroquinolones ndi mapiritsi otani?

Pakadali pano, mapiritsi amaperekedwa kupuma kwa fluoroquinolones kuti amenyane ndi matenda opatsirana kumtunda ndi m'munsi, mankhwala ochizira matenda opatsirana ndi ubongo chibayo. Pano pali mndandanda wa mankhwala ochepa omwe ali nawo mapiritsi:

• Levofloxacin;
• Moxifloxacin;
• Sparfloxacin;
• Norfloxacin ndi ena.

Musanayambe kuchipatala, phunzirani mosamalitsa zotsutsana - mankhwala ambiri a gululi sakuvomerezedwa kuti agwiritsidwe ntchito motsutsana ndi matenda opatsirana, impso ndi chiwindi. Kwa ana ndi amayi apakati, fluoroquinolones amawonetsedwa mosamalitsa malinga ndi lamulo la dokotala pankhani ya kusunga moyo.